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Mendeley readers
Attention Score in Context
| Title |
A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC
|
|---|---|
| Published in |
European Journal of Immunology, March 2009
|
| DOI | 10.1002/eji.200839116 |
| Pubmed ID | |
| Authors |
Kent S. Boles, William Vermi, Fabio Facchetti, Anja Fuchs, Timothy J. Wilson, Thomas G. Diacovo, Marina Cella, Marco Colonna |
| Abstract |
Nectins and Nectin-like molecules (Necl) play a critical role in cell polarity within epithelia and in the nervous and reproductive systems. Recently, immune receptors specific for Nectins/Necl have been described. Since the expression and distribution of Nectins/Necl is often subverted during tumorigenesis, it has been suggested that the immune system may use these receptors to recognize and eliminate tumors. Here we describe a novel immunoreceptor, Washington University Cell Adhesion Molecule, which is expressed on human follicular B helper T cells (TFH) and binds a Nectin/Necl family member, the poliovirus receptor (PVR), under both static and flow conditions. Furthermore, we demonstrate that PVR is abundantly expressed by follicular DC (FDC) within the germinal center. These results reveal a novel molecular interaction that mediates adhesion of TFH to FDC and provide the first evidence that immune receptors for Nectins/Necl may be involved the generation of T cell-dependent antibody responses. |
Mendeley readers
The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| United States | 2 | 1% |
| United Kingdom | 1 | <1% |
| Italy | 1 | <1% |
| Japan | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 147 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 19% |
| Researcher | 24 | 15% |
| Student > Master | 16 | 10% |
| Student > Bachelor | 12 | 8% |
| Student > Doctoral Student | 9 | 6% |
| Other | 21 | 14% |
| Unknown | 43 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 21% |
| Immunology and Microbiology | 28 | 18% |
| Medicine and Dentistry | 23 | 15% |
| Biochemistry, Genetics and Molecular Biology | 20 | 13% |
| Unspecified | 1 | <1% |
| Other | 7 | 5% |
| Unknown | 43 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2023.
All research outputs
#3,919,343
of 26,017,215 outputs
Outputs from European Journal of Immunology
#583
of 7,032 outputs
Outputs of similar age
#13,545
of 113,352 outputs
Outputs of similar age from European Journal of Immunology
#4
of 41 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,032 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,352 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.