| Title |
In vitro study of alginate–chitosan microcapsules: an alternative to liver cell transplants for the treatment of liver failure
|
|---|---|
| Published in |
Biotechnology Techniques, March 2005
|
| DOI | 10.1007/s10529-005-0687-3 |
| Pubmed ID | |
| Authors |
Tasima Haque, Hongmei Chen, Wei Ouyang, Christopher Martoni, Bisi Lawuyi, Aleksandra Malgorzata Urbanska, Satya Prakash |
| Abstract |
The application of alginate-chitosan (AC) microcapsules to liver cell transplantation has not been previously investigated. In the current in vitro study, we have investigated the potential of AC microcapsules for the encapsulation of liver cells and show that the AC membrane supports the survival, proliferation and protein secretion by entrapped hepatocytes. The AC membrane provides cell immuno-isolation and has the potential for cell cryopreservation. The AC microcapsule has several advantages compared to more widely used alginate-poly-L-lysine (APA) microcapsules for the application of cell therapy. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 2% |
| United Kingdom | 1 | 2% |
| Mexico | 1 | 2% |
| Unknown | 53 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 21% |
| Student > Master | 11 | 20% |
| Researcher | 8 | 14% |
| Student > Bachelor | 6 | 11% |
| Student > Doctoral Student | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 23% |
| Engineering | 8 | 14% |
| Medicine and Dentistry | 8 | 14% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Chemistry | 5 | 9% |
| Other | 3 | 5% |
| Unknown | 14 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 June 2019.
All research outputs
#2,863,994
of 25,374,917 outputs
Outputs from Biotechnology Techniques
#45
of 2,762 outputs
Outputs of similar age
#5,085
of 76,624 outputs
Outputs of similar age from Biotechnology Techniques
#1
of 26 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,762 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,624 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.