Title |
A Cytochrome b561 with Ferric Reductase Activity from the Parasitic Blood Fluke, Schistosoma japonicum
|
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Published in |
PLoS Neglected Tropical Diseases, November 2010
|
DOI | 10.1371/journal.pntd.0000884 |
Pubmed ID | |
Authors |
Amber Glanfield, Donald P. McManus, Danielle J. Smyth, Erica M. Lovas, Alex Loukas, Geoffrey N. Gobert, Malcolm K. Jones |
Abstract |
Iron has an integral role in numerous cellular reactions and is required by virtually all organisms. In physiological conditions, iron is abundant in a largely insoluble ferric state. Ferric reductases are an essential component of iron uptake by cells, reducing iron to the soluble ferrous form. Cytochromes b561 (cyts-b561) are a family of ascorbate reducing transmembrane proteins found in most eukaryotic cells. The identification of the ferric reductase duodenal cytochrome b (dcytb) and recent observations that other cyts-b561 may be involved in iron metabolism have opened novel perspectives for elucidating their physiological function. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 4% |
Unknown | 24 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 32% |
Student > Ph. D. Student | 5 | 20% |
Student > Bachelor | 3 | 12% |
Professor > Associate Professor | 2 | 8% |
Student > Master | 2 | 8% |
Other | 4 | 16% |
Unknown | 1 | 4% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 7 | 28% |
Environmental Science | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Neuroscience | 1 | 4% |
Other | 2 | 8% |
Unknown | 2 | 8% |