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A New Ceramide from Suillus luteus and Its Cytotoxic Activity against Human Melanoma Cells

Overview of attention for article published in Chemistry & Biodiversity, January 2008
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Mentioned by

wikipedia
1 Wikipedia page

Citations

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21 Dimensions

Readers on

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24 Mendeley
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Title
A New Ceramide from Suillus luteus and Its Cytotoxic Activity against Human Melanoma Cells
Published in
Chemistry & Biodiversity, January 2008
DOI 10.1002/cbdv.200890002
Pubmed ID
Authors

Francisco León, Ignacio Brouard, Fernando Torres, José Quintana, Augusto Rivera, Francisco Estévez, Jaime Bermejo

Abstract

A new phytosphingosine-type ceramide, suillumide (1), was isolated from the EtOH extract of the basidiomycete Suillus luteus (L.) S. F. Gray, along with ten known compounds: ergosta-4,6,8(14),22-tetraen-3-one, ergosterol, ergosterol peroxide, suillin, (E)-3,4,5-trimethoxycinnamic alcohol, 5 alpha,6 alpha-epoxyergosta-8,22-diene-3beta,7 beta-diol, (R)-1-palmitoylglycerol, ergosta-7,9(11),22-triene-3beta,5 alpha,6 beta-triol, cerevisterol, and 4-hydroxybenzoic acid. The structure of 1 was determined on the basis of spectroscopic and mass-spectrometric analyses, as well as by chemical methods. Compound 1 and its synthetic diacetyl derivative 2 were tested for their cytotoxic activities against the human melanoma cell line SK-MEL-1. Both drugs showed IC(50) values of ca. 10 microM after 72 h of exposure.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 4%
Spain 1 4%
Ecuador 1 4%
Unknown 21 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 33%
Student > Ph. D. Student 3 13%
Student > Bachelor 2 8%
Lecturer 1 4%
Student > Doctoral Student 1 4%
Other 4 17%
Unknown 5 21%
Readers by discipline Count As %
Chemistry 7 29%
Biochemistry, Genetics and Molecular Biology 4 17%
Agricultural and Biological Sciences 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Immunology and Microbiology 1 4%
Other 2 8%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2013.
All research outputs
#8,292,507
of 24,811,707 outputs
Outputs from Chemistry & Biodiversity
#291
of 2,786 outputs
Outputs of similar age
#45,762
of 167,151 outputs
Outputs of similar age from Chemistry & Biodiversity
#3
of 13 outputs
Altmetric has tracked 24,811,707 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,786 research outputs from this source. They receive a mean Attention Score of 2.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,151 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.