Title |
Brucella microti: the genome sequence of an emerging pathogen
|
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Published in |
BMC Genomics, August 2009
|
DOI | 10.1186/1471-2164-10-352 |
Pubmed ID | |
Authors |
Stéphane Audic, Magali Lescot, Jean-Michel Claverie, Holger C Scholz |
Abstract |
Using a combination of pyrosequencing and conventional Sanger sequencing, the complete genome sequence of the recently described novel Brucella species, Brucella microti, was determined. B. microti is a member of the genus Brucella within the Alphaproteobacteria, which consists of medically important highly pathogenic facultative intracellular bacteria. In contrast to all other Brucella species, B. microti is a fast growing and biochemically very active microorganism with a phenotype more similar to that of Ochrobactrum, a facultative human pathogen. The atypical phenotype of B. microti prompted us to look for genomic differences compared to other Brucella species and to look for similarities with Ochrobactrum. |
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