| Title |
Respiratory supercomplexes: structure, function and assembly
|
|---|---|
| Published in |
Protein & Cell, July 2013
|
| DOI | 10.1007/s13238-013-3032-y |
| Pubmed ID | |
| Authors |
Rasika Vartak, Christina Ann-Marie Porras, Yidong Bai |
| Abstract |
The mitochondrial respiratory chain consists of 5 enzyme complexes that are responsible for ATP generation. The paradigm of the electron transport chain as discrete enzymes diffused in the inner mitochondrial membrane has been replaced by the solid state supercomplex model wherein the respiratory complexes associate with each other to form supramolecular complexes. Defects in these supercomplexes, which have been shown to be functionally active and required for forming stable respiratory complexes, have been associated with many genetic and neurodegenerative disorders demonstrating their biomedical significance. In this review, we will summarize the functional and structural significance of supercomplexes and provide a comprehensive review of their assembly and the assembly factors currently known to play a role in this process. |
Mendeley readers
The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| France | 1 | <1% |
| Czechia | 1 | <1% |
| Russia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 128 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 40 | 30% |
| Student > Bachelor | 20 | 15% |
| Student > Master | 18 | 14% |
| Researcher | 15 | 11% |
| Student > Doctoral Student | 12 | 9% |
| Other | 11 | 8% |
| Unknown | 17 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 41 | 31% |
| Agricultural and Biological Sciences | 41 | 31% |
| Medicine and Dentistry | 11 | 8% |
| Chemistry | 7 | 5% |
| Neuroscience | 3 | 2% |
| Other | 8 | 6% |
| Unknown | 22 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2021.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from Protein & Cell
#284
of 738 outputs
Outputs of similar age
#65,096
of 194,542 outputs
Outputs of similar age from Protein & Cell
#3
of 13 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 738 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.4. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,542 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.