Title |
Bacterial Causes of Empyema in Children, Australia, 2007–2009 - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC
|
---|---|
Published in |
Emerging Infectious Diseases, October 2011
|
DOI | 10.3201/eid1710.101825 |
Pubmed ID | |
Authors |
Roxanne E. Strachan, Anita Cornelius, Gwendolyn L. Gilbert, Tanya Gulliver, Andrew Martin, Tim McDonald, Gillian M. Nixon, Rob Roseby, Sarath Ranganathan, Hiran Selvadurai, Greg Smith, Manuel Soto-Martinez, Sadasivam Suresh, Laurel Teoh, Kiran Thapa, Claire E. Wainwright, Adam Jaffé, on behalf of the Australian Research Network in Empyema |
Abstract |
An increase in the incidence of empyema worldwide could be related to invasive pneumococcal disease caused by emergent nonvaccine replacement serotypes. To determine bacterial pathogens and pneumococcal serotypes that cause empyema in children in Australia, we conducted a 2-year study of 174 children with empyema. Blood and pleural fluid samples were cultured, and pleural fluid was tested by PCR. Thirty-two (21.0%) of 152 blood and 53 (33.1%) of 160 pleural fluid cultures were positive for bacteria; Streptococcus pneumoniae was the most common organism identified. PCR identified S. pneumoniae in 74 (51.7%) and other bacteria in 19 (13.1%) of 145 pleural fluid specimens. Of 53 samples in which S. pneumoniae serotypes were identified, 2 (3.8%) had vaccine-related and 51 (96.2%) had nonvaccine serotypes; 19A (n = 20; 36.4%), 3 (n = 18; 32.7%), and 1 (n = 8; 14.5%) were the most common. High proportions of nonvaccine serotypes suggest the need to broaden vaccine coverage. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 2% |
Portugal | 1 | 2% |
Unknown | 43 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 20% |
Student > Bachelor | 8 | 18% |
Other | 6 | 13% |
Professor > Associate Professor | 5 | 11% |
Student > Ph. D. Student | 5 | 11% |
Other | 7 | 16% |
Unknown | 5 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 67% |
Nursing and Health Professions | 6 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 1 | 2% |
Unknown | 5 | 11% |