Title |
Differences Between Schizophrenic and Normal Subjects Using Network Properties from fMRI
|
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Published in |
Journal of Digital Imaging, September 2017
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DOI | 10.1007/s10278-017-0020-4 |
Pubmed ID | |
Authors |
Youngoh Bae, Kunaraj Kumarasamy, Issa M. Ali, Panagiotis Korfiatis, Zeynettin Akkus, Bradley J. Erickson |
Abstract |
Schizophrenia has been proposed to result from impairment of functional connectivity. We aimed to use machine learning to distinguish schizophrenic subjects from normal controls using a publicly available functional MRI (fMRI) data set. Global and local parameters of functional connectivity were extracted for classification. We found decreased global and local network connectivity in subjects with schizophrenia, particularly in the anterior right cingulate cortex, the superior right temporal region, and the inferior left parietal region as compared to healthy subjects. Using support vector machine and 10-fold cross-validation, nine features reached 92.1% prediction accuracy, respectively. Our results suggest that there are significant differences between control and schizophrenic subjects based on regional brain activity detected with fMRI. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 51 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 18% |
Student > Master | 7 | 14% |
Student > Ph. D. Student | 5 | 10% |
Student > Bachelor | 4 | 8% |
Student > Postgraduate | 4 | 8% |
Other | 8 | 16% |
Unknown | 14 | 27% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 25% |
Computer Science | 6 | 12% |
Engineering | 4 | 8% |
Neuroscience | 4 | 8% |
Physics and Astronomy | 2 | 4% |
Other | 5 | 10% |
Unknown | 17 | 33% |