| Title |
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
|
|---|---|
| Published in |
BMC Cancer, November 2009
|
| DOI | 10.1186/1471-2407-9-401 |
| Pubmed ID | |
| Authors |
Aaron L Sarver, Amy J French, Pedro M Borralho, Venugopal Thayanithy, Ann L Oberg, Kevin AT Silverstein, Bruce W Morlan, Shaun M Riska, Lisa A Boardman, Julie M Cunningham, Subbaya Subramanian, Liang Wang, Tom C Smyrk, Cecilia MP Rodrigues, Stephen N Thibodeau, Clifford J Steer |
| Abstract |
Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate gene expression. Differential miRNA expression in cancer versus normal tissue is a common event and may be pivotal for tumor onset and progression. |
Mendeley readers
The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Norway | 2 | 1% |
| Germany | 1 | <1% |
| Malaysia | 1 | <1% |
| Indonesia | 1 | <1% |
| Chile | 1 | <1% |
| Australia | 1 | <1% |
| Mexico | 1 | <1% |
| China | 1 | <1% |
| Spain | 1 | <1% |
| Other | 2 | 1% |
| Unknown | 127 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 32 | 23% |
| Student > Ph. D. Student | 30 | 22% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 13 | 9% |
| Professor > Associate Professor | 9 | 6% |
| Other | 20 | 14% |
| Unknown | 19 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 54 | 39% |
| Biochemistry, Genetics and Molecular Biology | 33 | 24% |
| Medicine and Dentistry | 25 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 1% |
| Chemistry | 2 | 1% |
| Other | 5 | 4% |
| Unknown | 18 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2018.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from BMC Cancer
#2,059
of 8,294 outputs
Outputs of similar age
#48,369
of 165,758 outputs
Outputs of similar age from BMC Cancer
#12
of 29 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,294 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,758 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.