Title |
Phylogenetic prediction of cis-acting elements: a cre-like sequence in Norovirus genome?
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Published in |
BMC Research Notes, September 2009
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DOI | 10.1186/1756-0500-2-176 |
Pubmed ID | |
Authors |
Matías Victoria, Rodney Colina, Marize Pereira Miagostovich, José P Leite, Juan Cristina |
Abstract |
Discrete RNA structures such as cis-acting replication elements (cre) in the coding region of RNA virus genomes create characteristic suppression of synonymous site variability (SSSV). Different phylogenetic methods have been developed to predict secondary structures in RNA viruses, for high-resolution thermodynamic scanning and for detecting SSSV. These approaches have been successfully in predicting cis-acting signals in different members of the family Picornaviridae and Caliciviridae. In order to gain insight into the identification of cis-acting signals in viruses whose mechanisms of replication are currently unknown, we performed a phylogenetic analysis of complete genome sequences from 49 Human Norovirus (NoV) strains. |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 5 | 17% |
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Immunology and Microbiology | 1 | 3% |
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