| Title |
A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey
|
|---|---|
| Published in |
Archives of Microbiology, February 2015
|
| DOI | 10.1007/s00203-015-1091-6 |
| Pubmed ID | |
| Authors |
Rowena Jenkins, Mandy Wootton, Robin Howe, Rose Cooper |
| Abstract |
Pseudomonas and Burkholderia pose a significant health threat to people with chronic respiratory conditions; the resistance inherent in these bacteria indicates that new antimicrobial strategies are required. Susceptibility of 56 strains of P. aeruginosa and 55 strains of Burkholderia to manuka honey, tobramycin and colistin using microbroth dilution and E strip was determined. MICs of antibiotics with honey were determined to search for synergistic combinations against two representative strains of each genus. All strains exhibited susceptibility to honey ≤10 % (w/v); mean susceptibility of Burkholderia (4.6 % w/v) was lower than P. aeruginosa (7.3 % w/v). Synergistic or additive combinations were found with all four strains tested. Combinations of manuka honey with antibiotics can be used to lower the MIC need to successfully inhibit both P. aeruginosa and B. cepacia. The use of honey as a combination agent may be possible for the management of P. aeruginosa and B. cepacia. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 15% |
| Student > Bachelor | 6 | 15% |
| Student > Master | 5 | 12% |
| Researcher | 5 | 12% |
| Student > Doctoral Student | 2 | 5% |
| Other | 6 | 15% |
| Unknown | 11 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 8 | 20% |
| Medicine and Dentistry | 6 | 15% |
| Agricultural and Biological Sciences | 3 | 7% |
| Nursing and Health Professions | 3 | 7% |
| Veterinary Science and Veterinary Medicine | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 15 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2020.
All research outputs
#1,436,075
of 23,572,509 outputs
Outputs from Archives of Microbiology
#17
of 2,896 outputs
Outputs of similar age
#21,969
of 362,323 outputs
Outputs of similar age from Archives of Microbiology
#1
of 18 outputs
Altmetric has tracked 23,572,509 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,896 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.