| Title |
Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study
|
|---|---|
| Published in |
Osteoporosis International, March 2018
|
| DOI | 10.1007/s00198-018-4490-0 |
| Pubmed ID | |
| Authors |
F. Johannesdottir, B. Allaire, D. E. Anderson, E. J. Samelson, D. P. Kiel, M. L. Bouxsein |
| Abstract |
Relative age-related deficit in trunk muscle density was greater in women than men whereas the relative decrease in muscle mass with age was similar in both sexes. The greater muscle fat content and greater age-related fat accumulation among women may contribute to women suffering more functional disabilities than men. A better understanding of the effect of aging on trunk musculature will have implications for physical function, disability, pain, and risk of injury in older adults. Thus, we determined the age- and sex-related differences in muscle density and size of both thoracic and lumbar trunk muscles. In this cross-sectional study, muscle density and size were measured from quantitative computed tomography (QCT) scans for 10 trunk muscle groups at different vertebral levels in 250 community-based men and women aged 40 to 90 years from the Framingham Offspring and Third Generation cohorts. Trunk muscles in men were 20-67% larger and had 5-68% higher density than in women. The relative age-related deficits in muscle size were similar in both sexes, and decreased on average by ~ 8% per decade in both sexes. In contrast, women had greater age-related decreases in muscle density than men (- 17% in women, and - 11% in men, p < 0.01). Age-related declines varied by specific muscle, tending to be greater for outer trunk muscles than for paraspinal muscles, but within a given muscle the age-related changes in muscle density and size were similar among spinal levels. This comprehensive study of trunk muscle deficits with increasing age may have important implications for physical function, disability, pain, and risk of injury in older adults. The greater levels of mobility impairments with aging in women may in part be explained by greater proportion of intramuscular fat tissue and greater age-related fat accumulation in trunk muscles in women than in men. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 20% |
| Netherlands | 1 | 20% |
| Mexico | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 64 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 11 | 17% |
| Student > Ph. D. Student | 10 | 16% |
| Researcher | 7 | 11% |
| Student > Postgraduate | 5 | 8% |
| Student > Master | 3 | 5% |
| Other | 7 | 11% |
| Unknown | 21 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 22% |
| Nursing and Health Professions | 5 | 8% |
| Engineering | 4 | 6% |
| Social Sciences | 4 | 6% |
| Neuroscience | 3 | 5% |
| Other | 9 | 14% |
| Unknown | 25 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2018.
All research outputs
#14,390,941
of 25,378,799 outputs
Outputs from Osteoporosis International
#2,014
of 3,858 outputs
Outputs of similar age
#165,234
of 338,922 outputs
Outputs of similar age from Osteoporosis International
#35
of 89 outputs
Altmetric has tracked 25,378,799 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,858 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
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We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.