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Respiratory arsenate reductase as a bidirectional enzyme

Overview of attention for article published in Biochemical & Biophysical Research Communications, March 2009
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Title
Respiratory arsenate reductase as a bidirectional enzyme
Published in
Biochemical & Biophysical Research Communications, March 2009
DOI 10.1016/j.bbrc.2009.03.045
Pubmed ID
Authors

Christine Richey, Peter Chovanec, Shelley E. Hoeft, Ronald S. Oremland, Partha Basu, John F. Stolz

Abstract

The haloalkaliphilic bacterium Alkalilimnicola ehrlichii is capable of anaerobic chemolithoautotrophic growth by coupling the oxidation of arsenite (As(III)) to the reduction of nitrate and carbon dioxide. Analysis of its complete genome indicates that it lacks a conventional arsenite oxidase (Aox), but instead possesses two operons that each encode a putative respiratory arsenate reductase (Arr). Here we show that one homolog is expressed under chemolithoautotrophic conditions and exhibits both arsenite oxidase and arsenate reductase activity. We also demonstrate that Arr from two arsenate respiring bacteria, Alkaliphilus oremlandii and Shewanella sp. strain ANA-3, is also biochemically reversible. Thus Arr can function as a reductase or oxidase. Its physiological role in a specific organism, however, may depend on the electron potentials of the molybdenum center and [Fe-S] clusters, additional subunits, or constitution of the electron transfer chain. This versatility further underscores the ubiquity and antiquity of microbial arsenic metabolism.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Colombia 1 1%
Portugal 1 1%
Unknown 81 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 24%
Student > Ph. D. Student 17 20%
Student > Master 11 13%
Student > Bachelor 6 7%
Student > Postgraduate 6 7%
Other 15 18%
Unknown 10 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 40%
Environmental Science 14 16%
Biochemistry, Genetics and Molecular Biology 13 15%
Engineering 3 4%
Chemistry 3 4%
Other 4 5%
Unknown 14 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2014.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Biochemical & Biophysical Research Communications
#7,621
of 26,637 outputs
Outputs of similar age
#38,770
of 109,697 outputs
Outputs of similar age from Biochemical & Biophysical Research Communications
#52
of 117 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 26,637 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,697 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.