| Title |
Citrulline and nitrogen homeostasis: an overview
|
|---|---|
| Published in |
Amino Acids, February 2015
|
| DOI | 10.1007/s00726-015-1932-2 |
| Pubmed ID | |
| Authors |
C. Breuillard, L. Cynober, C. Moinard |
| Abstract |
Citrulline (Cit) is a non-essential amino acid whose metabolic properties were largely ignored until the last decade when it began to emerge as a highly promising nutrient with many regulatory properties, with a key role in nitrogen homeostasis. Because Cit is not taken up by the liver, its synthesis from arginine, glutamine, ornithine and proline in the intestine prevents the hepatic uptake of the two first amino acids which activate the urea cycle and so prevents amino acid catabolism. This sparing effect may have positive spin-off for muscle via increased protein synthesis, protein content and functionality. However, the mechanisms of action of Cit are not fully known, even if preliminary data suggest an implication of mTOR pathway. Further exploration is needed to gain a complete overview of the role of Cit in the control of nitrogen homeostasis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 115 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 22 | 19% |
| Student > Ph. D. Student | 17 | 15% |
| Student > Master | 17 | 15% |
| Researcher | 7 | 6% |
| Other | 7 | 6% |
| Other | 17 | 15% |
| Unknown | 30 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 15% |
| Biochemistry, Genetics and Molecular Biology | 17 | 15% |
| Medicine and Dentistry | 14 | 12% |
| Sports and Recreations | 8 | 7% |
| Nursing and Health Professions | 5 | 4% |
| Other | 21 | 18% |
| Unknown | 34 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2023.
All research outputs
#2,061,801
of 23,565,002 outputs
Outputs from Amino Acids
#108
of 1,540 outputs
Outputs of similar age
#31,528
of 362,007 outputs
Outputs of similar age from Amino Acids
#3
of 36 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,540 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,007 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.