| Title |
Update on the Therapeutic Management of Hepatic Encephalopathy
|
|---|---|
| Published in |
Current Gastroenterology Reports, April 2018
|
| DOI | 10.1007/s11894-018-0627-8 |
| Pubmed ID | |
| Authors |
Linda Skibsted Kornerup, Lise Lotte Gluud, Hendrik Vilstrup, Gitte Dam |
| Abstract |
Hepatic encephalopathy (HE) is a common and devastating complication to chronic liver disease. In this paper, we summarize the latest research and evidence of both conventional and up-coming treatments. Meta-analyses report beneficial effects of lactulose, branched-chain amino acids, rifaximin, and to some degree L-ornithine L-aspartate on the manifestations of HE in patients with cirrhosis, and generally the numbers needed to treat are low. Recent studies on newer HE treatments including ornithine phenylacetate, spherical carbon, and fecal microbiota transplant also report potentially beneficial effects on HE manifestations. The conventional treatments benefit patients with HE. Newer treatments are under study and more research is needed for their validation. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 17% |
| Canada | 1 | 17% |
| India | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 127 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 15% |
| Student > Bachelor | 12 | 9% |
| Researcher | 11 | 9% |
| Student > Postgraduate | 11 | 9% |
| Student > Doctoral Student | 11 | 9% |
| Other | 25 | 20% |
| Unknown | 38 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 50 | 39% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 11% |
| Agricultural and Biological Sciences | 6 | 5% |
| Nursing and Health Professions | 5 | 4% |
| Biochemistry, Genetics and Molecular Biology | 3 | 2% |
| Other | 8 | 6% |
| Unknown | 41 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2022.
All research outputs
#7,295,931
of 25,461,852 outputs
Outputs from Current Gastroenterology Reports
#126
of 368 outputs
Outputs of similar age
#119,540
of 343,489 outputs
Outputs of similar age from Current Gastroenterology Reports
#1
of 1 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 368 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,489 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them