| Title |
The Impact of Obesity on Breast Cancer
|
|---|---|
| Published in |
Current Oncology Reports, April 2018
|
| DOI | 10.1007/s11912-018-0688-8 |
| Pubmed ID | |
| Authors |
Daniel F. Argolo, Clifford A. Hudis, Neil M. Iyengar |
| Abstract |
The rates of obesity are increasing worldwide and this condition is now recognized as a leading preventable cause of cancer. Several diseases are directly related to obesity, including diabetes, hypertension, atherosclerosis, stroke, musculoskeletal disorders, and a diverse range of malignances-such as breast cancer. Obesity is associated with an increased risk of postmenopausal estrogen receptor-positive breast cancer and worse cancer-related outcomes for all breast tumor subtypes. Several mechanisms have been proposed to contribute to the obesity-cancer link, including high levels of circulating and local estrogens, altered amounts of adipokines (leptin and adiponectin), disrupted insulin/IGF signaling, modifications within the microbiome, and local and systemic effects of inflammation. Here we will review recent advances in our understanding of the complex signaling pathways underlying the obesity-cancer link. An improved understanding of these processes is anticipated to propel novel and effective intervention strategies to reduce the global obesity-cancer burden. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 185 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 24 | 13% |
| Student > Master | 21 | 11% |
| Student > Ph. D. Student | 17 | 9% |
| Student > Doctoral Student | 14 | 8% |
| Researcher | 13 | 7% |
| Other | 27 | 15% |
| Unknown | 69 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 44 | 24% |
| Biochemistry, Genetics and Molecular Biology | 20 | 11% |
| Nursing and Health Professions | 14 | 8% |
| Agricultural and Biological Sciences | 10 | 5% |
| Immunology and Microbiology | 4 | 2% |
| Other | 20 | 11% |
| Unknown | 73 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2019.
All research outputs
#18,603,172
of 23,043,346 outputs
Outputs from Current Oncology Reports
#670
of 890 outputs
Outputs of similar age
#255,517
of 329,173 outputs
Outputs of similar age from Current Oncology Reports
#20
of 28 outputs
Altmetric has tracked 23,043,346 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 890 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.