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Cadherin junctions and their cytoskeleton(s)

Overview of attention for article published in Current Opinion in Cell Biology, November 2012
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Title
Cadherin junctions and their cytoskeleton(s)
Published in
Current Opinion in Cell Biology, November 2012
DOI 10.1016/j.ceb.2012.10.010
Pubmed ID
Authors

William M Brieher, Alpha S Yap

Abstract

Classical cadherin adhesion receptors exert many of their biological effects through close cooperation with the cytoskeleton. Much attention has focused on attempting to understand the physical interactions between cadherin molecular complexes and cortical actin filaments. In this review we aim to draw attention to other issues that highlight the diverse and dynamic cytoskeletons that contribute to cadherin function. First, we discuss the regulation of actin filament dynamics in the cadherin-based junctional cytoskeleton, focusing on the emerging role of Arp2/3 as a junctional actin nucleator and its implications for actin homeostasis at junctions. Second, we review recent developments in understanding the impact of microtubules on cadherin function. Together, these emphasize that cadherins cooperate with multiple dynamic cytoskeletal networks at cell-cell junctions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 162 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Netherlands 1 <1%
Australia 1 <1%
Germany 1 <1%
Costa Rica 1 <1%
Singapore 1 <1%
Taiwan 1 <1%
United States 1 <1%
Unknown 153 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 28%
Researcher 34 21%
Student > Bachelor 20 12%
Student > Master 14 9%
Professor > Associate Professor 10 6%
Other 21 13%
Unknown 18 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 75 46%
Biochemistry, Genetics and Molecular Biology 32 20%
Medicine and Dentistry 8 5%
Engineering 7 4%
Chemistry 7 4%
Other 10 6%
Unknown 23 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2015.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Current Opinion in Cell Biology
#1,814
of 1,905 outputs
Outputs of similar age
#180,925
of 201,743 outputs
Outputs of similar age from Current Opinion in Cell Biology
#12
of 14 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,905 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,743 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.