| Title |
Ab ovo or de novo? Mechanisms of Centriole Duplication
|
|---|---|
| Published in |
Molecules & Cells, February 2009
|
| DOI | 10.1007/s10059-009-0017-z |
| Pubmed ID | |
| Authors |
Jadranka Loncarek, Alexey Khodjakov |
| Abstract |
The centrosome, an organelle comprising centrioles and associated pericentriolar material, is the major microtubule organizing center in animal cells. For the cell to form a bipolar mitotic spindle and ensure proper chromosome segregation at the end of each cell cycle, it is paramount that the cell contains two and only two centrosomes. Because the number of centrosomes in the cell is determined by the number of centrioles, cells have evolved elaborate mechanisms to control centriole biogenesis and to tightly coordinate this process with DNA replication. Here we review key proteins involved in centriole assembly, compare two major modes of centriole biogenesis, and discuss the mechanisms that ensure stringency of centriole number. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Switzerland | 2 | 2% |
| Germany | 1 | <1% |
| Russia | 1 | <1% |
| France | 1 | <1% |
| Unknown | 100 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 31% |
| Student > Ph. D. Student | 29 | 27% |
| Student > Bachelor | 8 | 7% |
| Student > Master | 6 | 6% |
| Professor > Associate Professor | 5 | 5% |
| Other | 9 | 8% |
| Unknown | 17 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 56 | 52% |
| Biochemistry, Genetics and Molecular Biology | 26 | 24% |
| Medicine and Dentistry | 4 | 4% |
| Computer Science | 1 | <1% |
| Social Sciences | 1 | <1% |
| Other | 3 | 3% |
| Unknown | 16 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2022.
All research outputs
#7,968,106
of 25,394,764 outputs
Outputs from Molecules & Cells
#147
of 877 outputs
Outputs of similar age
#36,655
of 109,413 outputs
Outputs of similar age from Molecules & Cells
#2
of 9 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 877 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,413 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.