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Infertility and incident endometrial cancer risk: a pooled analysis from the epidemiology of endometrial cancer consortium (E2C2)

Overview of attention for article published in British Journal of Cancer, February 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

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1 news outlet
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Citations

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44 Dimensions

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84 Mendeley
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Title
Infertility and incident endometrial cancer risk: a pooled analysis from the epidemiology of endometrial cancer consortium (E2C2)
Published in
British Journal of Cancer, February 2015
DOI 10.1038/bjc.2015.24
Pubmed ID
Authors

H P Yang, L S Cook, E Weiderpass, H-O Adami, K E Anderson, H Cai, J R Cerhan, T V Clendenen, A S Felix, C M Friedenreich, M Garcia-Closas, M T Goodman, X Liang, J Lissowska, L Lu, A M Magliocco, S E McCann, K B Moysich, S H Olson, S Petruzella, M C Pike, S Polidoro, F Ricceri, H A Risch, C Sacerdote, V W Setiawan, X O Shu, A B Spurdle, B Trabert, P M Webb, N Wentzensen, Y-B Xiang, Y Xu, H Yu, A Zeleniuch-Jacquotte, L A Brinton

Abstract

Background:Nulliparity is an endometrial cancer risk factor, but whether or not this association is due to infertility is unclear. Although there are many underlying infertility causes, few studies have assessed risk relations by specific causes.Methods:We conducted a pooled analysis of 8153 cases and 11 713 controls from 2 cohort and 12 case-control studies. All studies provided self-reported infertility and its causes, except for one study that relied on data from national registries. Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI).Results:Nulliparous women had an elevated endometrial cancer risk compared with parous women, even after adjusting for infertility (OR=1.76; 95% CI: 1.59-1.94). Women who reported infertility had an increased risk compared with those without infertility concerns, even after adjusting for nulliparity (OR=1.22; 95% CI: 1.13-1.33). Among women who reported infertility, none of the individual infertility causes were substantially related to endometrial cancer.Conclusions:Based on mainly self-reported infertility data that used study-specific definitions of infertility, nulliparity and infertility appeared to independently contribute to endometrial cancer risk. Understanding residual endometrial cancer risk related to infertility, its causes and its treatments may benefit from large studies involving detailed data on various infertility parameters.British Journal of Cancer advance online publication, 17 February 2015; doi:10.1038/bjc.2015.24 www.bjcancer.com.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 83 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 14%
Researcher 9 11%
Student > Master 7 8%
Student > Bachelor 6 7%
Other 6 7%
Other 12 14%
Unknown 32 38%
Readers by discipline Count As %
Medicine and Dentistry 27 32%
Biochemistry, Genetics and Molecular Biology 5 6%
Agricultural and Biological Sciences 4 5%
Environmental Science 3 4%
Nursing and Health Professions 3 4%
Other 7 8%
Unknown 35 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2016.
All research outputs
#2,700,278
of 22,792,160 outputs
Outputs from British Journal of Cancer
#1,651
of 10,417 outputs
Outputs of similar age
#35,100
of 255,126 outputs
Outputs of similar age from British Journal of Cancer
#73
of 149 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,417 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,126 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.