Title |
Human Monoclonal Antibody Fragments Targeting Matrilin-3 in Growth Plate Cartilage
|
---|---|
Published in |
Pharmaceutical Research, February 2015
|
DOI | 10.1007/s11095-015-1636-z |
Pubmed ID | |
Authors |
Crystal Sao-Fong Cheung, Zhongyu Zhu, Julian Chun-Kin Lui, Dimiter Dimitrov, Jeffrey Baron |
Abstract |
Many genetic disorders, including chondrodysplasias, and acquired disorders impair growth plate function, resulting in short and sometimes malformed bones. There are multiple endocrine and paracrine factors that promote chondrogenesis at the growth plate, which could potentially be used to treat these disorders. Targeting these growth factors specifically to the growth plate might augment the therapeutic skeletal effect while diminishing undesirable effects on non-target tissues. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 25% |
Other | 2 | 25% |
Lecturer > Senior Lecturer | 1 | 13% |
Student > Ph. D. Student | 1 | 13% |
Student > Postgraduate | 1 | 13% |
Other | 0 | 0% |
Unknown | 1 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 50% |
Nursing and Health Professions | 1 | 13% |
Agricultural and Biological Sciences | 1 | 13% |
Chemistry | 1 | 13% |
Unknown | 1 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2015.
All research outputs
#20,262,276
of 22,792,160 outputs
Outputs from Pharmaceutical Research
#2,645
of 2,856 outputs
Outputs of similar age
#214,945
of 255,121 outputs
Outputs of similar age from Pharmaceutical Research
#32
of 37 outputs
Altmetric has tracked 22,792,160 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,121 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.