Title |
Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections
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Published in |
Intensive Care Medicine, December 2013
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DOI | 10.1007/s00134-013-3163-x |
Pubmed ID | |
Authors |
David Grimaldi, Lionel Le Bourhis, Bertrand Sauneuf, Agnès Dechartres, Christophe Rousseau, Fatah Ouaaz, Maud Milder, Delphine Louis, Jean-Daniel Chiche, Jean-Paul Mira, Olivier Lantz, Frédéric Pène |
Abstract |
In between innate and adaptive immunity, the recently identified innate-like mucosal-associated invariant T (MAIT) lymphocytes display specific reactivity to non-streptococcal bacteria. Whether they are involved in bacterial sepsis has not been investigated. We aimed to assess the number and the time course of circulating innate-like T lymphocytes (MAIT, NKT and γδ T cells) in critically ill septic and non-septic patients and to establish correlations with the further development of intensive care unit (ICU)-acquired infections. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Switzerland | 1 | <1% |
Unknown | 112 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 34 | 30% |
Researcher | 14 | 12% |
Student > Master | 11 | 10% |
Student > Bachelor | 11 | 10% |
Student > Doctoral Student | 6 | 5% |
Other | 22 | 19% |
Unknown | 16 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 28 | 25% |
Medicine and Dentistry | 28 | 25% |
Immunology and Microbiology | 21 | 18% |
Biochemistry, Genetics and Molecular Biology | 11 | 10% |
Nursing and Health Professions | 4 | 4% |
Other | 3 | 3% |
Unknown | 19 | 17% |