Title |
Granulocyte Colony-Stimulating Factor and an In Vitro Whole Blood Model of Melioidosis
|
---|---|
Published in |
European Journal of Clinical Microbiology & Infectious Diseases, February 2004
|
DOI | 10.1007/s10096-003-1088-y |
Pubmed ID | |
Authors |
A. C. Cheng, P. Dasari, B. J. Currie |
Abstract |
The study reported here was conducted in order to explore the mechanism of action of granulocyte colony-stimulating factor (G-CSF) in the treatment of Burkholderia pseudomallei infections (otherwise known as melioidosis). Use of G-CSF as an adjunct to antibiotics has been associated with decreasing mortality among patients with melioidosis in the tropical region of the Northern Territory of Australia. However, using an in vitro whole blood assay, no significant difference was detected in the bactericidal activity of samples obtained from dialysis patients, patients with type 2 diabetes mellitus and healthy controls, and there was no improvement following coincubation with G-CSF. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 2 | 14% |
Other | 1 | 7% |
Student > Master | 1 | 7% |
Student > Bachelor | 1 | 7% |
Researcher | 1 | 7% |
Other | 1 | 7% |
Unknown | 7 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 21% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Environmental Science | 1 | 7% |
Decision Sciences | 1 | 7% |
Agricultural and Biological Sciences | 1 | 7% |
Other | 0 | 0% |
Unknown | 7 | 50% |