| Title |
Effects of physical exercise after treatment of early breast cancer: systematic review and meta-analysis
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, April 2018
|
| DOI | 10.1007/s10549-018-4786-y |
| Pubmed ID | |
| Authors |
Frederico Soares Falcetta, Henrique de Araújo Vianna Träsel, Fernando Kude de Almeida, Mariana Rangel Ribeiro Falcetta, Maicon Falavigna, Daniela Dornelles Rosa |
| Abstract |
Randomized clinical trials are inconclusive regarding the role of physical exercise in anthropometric measurements, quality of life, and survival in breast cancer patients. Our aim was to conduct a systematic review and meta-analysis to assess the effects of physical exercise on these outcomes in women who went through curative treatment of early-stage breast cancer. Pubmed, Embase, Cochrane Library were searched for randomized clinical trial comparing physical exercise (counseling or structured programs with supervised/individualized exercise sessions) with usual care in women that went through for breast cancer treatment. Primary outcomes were overall survival and disease-free survival, while secondary outcomes were weight loss, body mass index, waist-hip ratio, percentage of body fat, and quality of life. We found 60 randomized clinical trials, only one of them showed mortality data; the HR for mortality was 0.45 (95% CI 0.21-0.97) for the intervention group when compared to the control group. Physical exercise was associated with weight reduction (- 1.36 kg, 95% CI - 2.51 to - 0.21, p = 0.02), lower body mass index (- 0.89 kg/m2, 95% CI - 1.50 to - 0.28, p < 0.01), and lower percentage of body fat (- 1.60 percentage points, 95% CI - 2.31 to - 0.88, p < 0.01). There was an increase in the quality of life (standardized mean difference of 0.45, 95% CI 0.20-0.69, p < 0.01). The articles found had heterogeneous types of intervention, but they showed significant effects on anthropometric measures and quality of life. Among them, only one study had mortality as outcome and it showed physical exercise as a protective intervention. Despite these findings, publication bias and poor methodological quality were presented. Physical exercise should be advised for breast cancer survivors since it has no adverse effects and can improve anthropometrics measures and quality of life. PROSPERO registry: CRD42014008743. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 18% |
| Saudi Arabia | 1 | 6% |
| India | 1 | 6% |
| Spain | 1 | 6% |
| Argentina | 1 | 6% |
| Germany | 1 | 6% |
| Italy | 1 | 6% |
| Canada | 1 | 6% |
| Australia | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 6 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 88% |
| Practitioners (doctors, other healthcare professionals) | 1 | 6% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 160 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 160 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 23 | 14% |
| Student > Bachelor | 15 | 9% |
| Researcher | 14 | 9% |
| Student > Ph. D. Student | 12 | 8% |
| Other | 10 | 6% |
| Other | 26 | 16% |
| Unknown | 60 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 27 | 17% |
| Medicine and Dentistry | 25 | 16% |
| Sports and Recreations | 20 | 13% |
| Psychology | 8 | 5% |
| Social Sciences | 6 | 4% |
| Other | 9 | 6% |
| Unknown | 65 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2023.
All research outputs
#3,489,437
of 23,968,814 outputs
Outputs from Breast Cancer Research and Treatment
#579
of 4,814 outputs
Outputs of similar age
#70,248
of 331,398 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#9
of 55 outputs
Altmetric has tracked 23,968,814 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,814 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,398 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.