Title |
Virulent T4 Acanthamoeba causing keratitis in a patient after swimming while wearing contact lenses in Southern Brazil
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Published in |
Acta Parasitologica, April 2018
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DOI | 10.1515/ap-2018-0050 |
Pubmed ID | |
Authors |
Laura Fuhrich Fabres, Vinicius José Maschio, Denise Leal dos Santos, Sergio Kwitko, Diane Ruschel Marinho, Bruno Schneider de Araújo, Claudete Inês Locatelli, Marilise Brittes Rott |
Abstract |
Several strains of free-living amoebae belonging to the genus Acanthamoeba can cause a painful sight-threatening disease of the cornea known as Acanthamoeba keratitis (AK). The numbers of AK cases keep rising worldwide mainly due to an increase in contact lens wearers and lack of hygiene in the maintenance of contact lenses and their cases. We report a case of AK in a healthy young woman admitted to the Hospital de Clinicas in Porto Alegre, southern Brazil. Corneal scrapings were examined for the presence of Acanthamoeba strains. The initial isolate was characterized by morphological and genotypic properties. The isolate belonged to group III according to Pussard and Pons' cyst morphology. Analysis of its 18S rDNA sequence identified the isolate as genotype T4. The T4 genotype is the most commonly reported among keratitis isolates and the most common in environmental samples. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 5 | 21% |
Student > Bachelor | 4 | 17% |
Student > Doctoral Student | 3 | 13% |
Professor | 2 | 8% |
Professor > Associate Professor | 2 | 8% |
Other | 2 | 8% |
Unknown | 6 | 25% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 3 | 13% |
Medicine and Dentistry | 3 | 13% |
Nursing and Health Professions | 3 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Other | 5 | 21% |
Unknown | 6 | 25% |