| Title |
A common variant upstream of the PAX6 gene influences islet function in man
|
|---|---|
| Published in |
Diabetologia, September 2011
|
| DOI | 10.1007/s00125-011-2300-8 |
| Pubmed ID | |
| Authors |
E. Ahlqvist, F. Turrini, S. T. Lang, J. Taneera, Y. Zhou, P. Almgren, O. Hansson, B. Isomaa, T. Tuomi, K. Eriksson, J. G. Eriksson, V. Lyssenko, L. Groop |
| Abstract |
Impaired glucose tolerance and impaired insulin secretion have been reported in families with PAX6 mutations and it is suggested that they result from defective proinsulin processing due to lack of prohormone convertase 1/3, encoded by PCSK1. We investigated whether a common PAX6 variant would mimic these findings and explored in detail its effect on islet function in man. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 43 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 24% |
| Student > Ph. D. Student | 6 | 13% |
| Professor | 4 | 9% |
| Student > Master | 3 | 7% |
| Student > Doctoral Student | 2 | 4% |
| Other | 8 | 17% |
| Unknown | 12 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 24% |
| Biochemistry, Genetics and Molecular Biology | 8 | 17% |
| Agricultural and Biological Sciences | 7 | 15% |
| Nursing and Health Professions | 2 | 4% |
| Unspecified | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 15 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2011.
All research outputs
#18,295,723
of 22,651,245 outputs
Outputs from Diabetologia
#4,664
of 5,023 outputs
Outputs of similar age
#95,037
of 114,471 outputs
Outputs of similar age from Diabetologia
#42
of 48 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
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We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.