You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman Primates
|
|---|---|
| Published in |
Journal of Infectious Diseases, March 2015
|
| DOI | 10.1093/infdis/jiv019 |
| Pubmed ID | |
| Authors |
Oleg V. Pyankov, Sergey A. Bodnev, Olga G. Pyankova, Vladislav V. Solodkyi, Stepan A. Pyankov, Yin Xiang Setoh, Valentina A. Volchkova, Andreas Suhrbier, Viktor V. Volchkov, Alexander A. Agafonov, Alexander A. Khromykh |
| Abstract |
The current unprecedented outbreak of Ebola virus (EBOV) disease in West Africa has demonstrated the urgent need for a vaccine. Here, we describe the evaluation of an EBOV vaccine candidate based on Kunjin replicon virus-like particles (KUN VLPs) encoding EBOV glycoprotein with a D637L mutation (GP/D637L) in nonhuman primates. Four African green monkeys (Cercopithecus aethiops) were injected subcutaneously with a dose of 10(9) KUN VLPs per animal twice with an interval of 4 weeks, and animals were challenged 3 weeks later intramuscularly with 600 plaque-forming units of Zaire EBOV. Three animals were completely protected against EBOV challenge, while one vaccinated animal and the control animal died from infection. We suggest that KUN VLPs encoding GP/D637L represent a viable EBOV vaccine candidate. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 56 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 20% |
| Student > Bachelor | 8 | 14% |
| Student > Master | 7 | 13% |
| Professor | 5 | 9% |
| Student > Ph. D. Student | 4 | 7% |
| Other | 8 | 14% |
| Unknown | 13 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 21% |
| Medicine and Dentistry | 7 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Veterinary Science and Veterinary Medicine | 3 | 5% |
| Immunology and Microbiology | 3 | 5% |
| Other | 7 | 13% |
| Unknown | 19 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2015.
All research outputs
#1,892,565
of 25,377,790 outputs
Outputs from Journal of Infectious Diseases
#1,418
of 14,793 outputs
Outputs of similar age
#23,402
of 271,147 outputs
Outputs of similar age from Journal of Infectious Diseases
#6
of 136 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,793 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,147 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.