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Review: Pharmacodynamic monitoring of immunosuppression in kidney transplantation

Overview of attention for article published in Nephrology, May 2010
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Title
Review: Pharmacodynamic monitoring of immunosuppression in kidney transplantation
Published in
Nephrology, May 2010
DOI 10.1111/j.1440-1797.2010.01349.x
Pubmed ID
Authors

KATHERINE A BARRACLOUGH, CHRISTINE E STAATZ, NICOLE M ISBEL, STEVEN J MCTAGGART

Abstract

Advances in immunosuppressive therapies have improved kidney transplant outcomes. However, immunosuppressant drug-induced toxicities continue to reduce tolerability and impact patient and graft survival. A major ongoing challenge in kidney transplantation is to establish ways of tailoring immunosuppressant therapy so as to maintain efficacy while minimizing toxicity. Pharmacodynamic monitoring by direct measurement of immune cell function has the potential to personalize immunosuppression. The purpose of this review is to provide the clinician with an overview of the methodology and use of immune function monitoring in the field of kidney transplantation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 15%
Student > Master 3 15%
Other 2 10%
Student > Bachelor 2 10%
Student > Postgraduate 2 10%
Other 7 35%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 11 55%
Pharmacology, Toxicology and Pharmaceutical Science 5 25%
Agricultural and Biological Sciences 2 10%
Immunology and Microbiology 1 5%
Unknown 1 5%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 March 2015.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Nephrology
#785
of 1,037 outputs
Outputs of similar age
#94,475
of 104,210 outputs
Outputs of similar age from Nephrology
#13
of 15 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,037 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,210 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.