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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Global Epidemiology of Pediatric Severe Sepsis: The Sepsis Prevalence, Outcomes, and Therapies Study
|
|---|---|
| Published in |
American Journal of Respiratory & Critical Care Medicine, May 2015
|
| DOI | 10.1164/rccm.201412-2323oc |
| Pubmed ID | |
| Authors |
Scott L. Weiss, Julie C. Fitzgerald, John Pappachan, Derek Wheeler, Juan C. Jaramillo-Bustamante, Asma Salloo, Sunit C. Singhi, Simon Erickson, Jason A. Roy, Jenny L. Bush, Vinay M. Nadkarni, Neal J. Thomas |
| Abstract |
Rationale: Limited data exist about the international burden of severe sepsis in critically ill children. Objectives: To characterize the global prevalence, therapies, and outcomes of severe sepsis in pediatric intensive care units to better inform interventional trials. Methods: Point prevalence study conducted on 5 days throughout 2013-2014 in 128 sites from 26 countries. Patients <18 years with severe sepsis defined by consensus criteria were included. Outcomes were severe sepsis point prevalence, therapies used, new or progressive multi-organ dysfunction, ventilator- and vasoactive-free days at day 28, functional status, and mortality. Measurements and Main Results: Of 6925 patients screened, 569 had severe sepsis (prevalence 8.2%, 95% CI 7.6, 8.9%). Median age was 3.0 (IQR 0.7-11.0) years. The most frequent sites of infection were respiratory (40%) and bloodstream (19%). Common therapies included mechanical ventilation (74% of patients), vasoactive infusions (55%), and corticosteroids (45%). Hospital mortality was 25% and did not differ by age or between developed and resource-limited countries. Median ventilator-free days were 16 (IQR 0-25) and vasoactive-free days were 23 (IQR 12-28). Sixty-seven percent had multi-organ dysfunction at sepsis recognition, with 30% subsequently developing new or progressive multi-organ dysfunction. Amongst survivors, 17% developed at least moderate disability. Sample sizes to detect a 5-10% absolute risk reduction in outcomes within interventional trials are estimated between 165-1437 patients per group. Conclusions: Pediatric severe sepsis remains a burdensome public health problem, with prevalence, morbidity, and mortality rates similar to reports from critically ill adult populations. International clinical trials targeting children with severe sepsis are warranted. |
X Demographics
The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 8 | 20% |
| United States | 7 | 17% |
| Australia | 3 | 7% |
| Chile | 1 | 2% |
| Malaysia | 1 | 2% |
| Mexico | 1 | 2% |
| Canada | 1 | 2% |
| Spain | 1 | 2% |
| Ireland | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 17 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 54% |
| Practitioners (doctors, other healthcare professionals) | 10 | 24% |
| Scientists | 7 | 17% |
| Science communicators (journalists, bloggers, editors) | 2 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 707 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| Canada | 1 | <1% |
| Australia | 1 | <1% |
| Egypt | 1 | <1% |
| Unknown | 703 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 78 | 11% |
| Student > Master | 76 | 11% |
| Student > Postgraduate | 74 | 10% |
| Researcher | 73 | 10% |
| Student > Bachelor | 69 | 10% |
| Other | 150 | 21% |
| Unknown | 187 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 365 | 52% |
| Nursing and Health Professions | 30 | 4% |
| Agricultural and Biological Sciences | 18 | 3% |
| Biochemistry, Genetics and Molecular Biology | 16 | 2% |
| Immunology and Microbiology | 12 | 2% |
| Other | 56 | 8% |
| Unknown | 210 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2022.
All research outputs
#964,343
of 25,711,518 outputs
Outputs from American Journal of Respiratory & Critical Care Medicine
#740
of 12,592 outputs
Outputs of similar age
#11,430
of 280,180 outputs
Outputs of similar age from American Journal of Respiratory & Critical Care Medicine
#11
of 107 outputs
Altmetric has tracked 25,711,518 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,592 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,180 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 107 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.