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Syntaxin1A-mediated Resistance and Hypersensitivity to Isoflurane in Drosophila melanogaster

Overview of attention for article published in Anesthesiology, May 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Citations

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27 Dimensions

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22 Mendeley
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Title
Syntaxin1A-mediated Resistance and Hypersensitivity to Isoflurane in Drosophila melanogaster
Published in
Anesthesiology, May 2015
DOI 10.1097/aln.0000000000000629
Pubmed ID
Authors

Oressia H. Zalucki, Hareesh Menon, Benjamin Kottler, Richard Faville, Rebecca Day, Adekunle T. Bademosi, Nickolas Lavidis, Shanker Karunanithi, Bruno van Swinderen

Abstract

Recent evidence suggests that general anesthetics activate endogenous sleep pathways, yet this mechanism cannot explain the entirety of general anesthesia. General anesthetics could disrupt synaptic release processes, as previous work in Caenorhabditis elegans and in vitro cell preparations suggested a role for the soluble NSF attachment protein receptor protein, syntaxin1A, in mediating resistance to several general anesthetics. The authors questioned whether the syntaxin1A-mediated effects found in these reductionist systems reflected a common anesthetic mechanism distinct from sleep-related processes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 27%
Student > Ph. D. Student 3 14%
Professor > Associate Professor 2 9%
Student > Bachelor 2 9%
Professor 1 5%
Other 1 5%
Unknown 7 32%
Readers by discipline Count As %
Neuroscience 8 36%
Agricultural and Biological Sciences 3 14%
Arts and Humanities 1 5%
Psychology 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Other 2 9%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2018.
All research outputs
#1,550,619
of 25,377,790 outputs
Outputs from Anesthesiology
#593
of 6,641 outputs
Outputs of similar age
#19,178
of 278,918 outputs
Outputs of similar age from Anesthesiology
#4
of 66 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,641 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.