| Title |
Knowing left from right: asymmetric functional connectivity during resting state
|
|---|---|
| Published in |
Brain Structure and Function, January 2018
|
| DOI | 10.1007/s00429-017-1604-y |
| Pubmed ID | |
| Authors |
Mathijs Raemaekers, Wouter Schellekens, Natalia Petridou, Nick F. Ramsey |
| Abstract |
The functional organization of left and right hemispheres is different, and hemispheric asymmetries are thought to underlie variations in brain function across individuals. In this study, we assess how differences between hemispheres are reflected in Asymmetric Functional Connectivity (AFC), which provides a full description of how the brain's connectivity structure during resting state differs from that of the same brain mirrored over the longitudinal fissure. In addition, we assess how AFC varies across subjects. Data were provided by the Human Connectome Project, including 423 resting state and combined language task fMRI data sets, and the pattern of AFC was established for all subjects. While we could quantify the symmetry of brain connectivity at 95%, significant asymmetries were observed, consisting foremost of: (1) higher correlations between language areas in the left hemisphere than between their right hemisphere homologues. (2) Higher correlations between language homologue areas in the right hemisphere and left default mode network, than between language areas in the left hemisphere and the default mode network in the right hemisphere. The extent to which subjects exhibited this pattern correlated with language lateralization and handedness. Further exploration in intersubject variation in AFC revealed several additional patterns, one involving entire hemispheres, and another correlations with limbic areas. These results show that language is an important, but not only determinant of AFC. The additional patterns of AFC require further research to be linked to specific asymmetric neuronal states or events. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 75% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 22% |
| Student > Ph. D. Student | 17 | 20% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 6 | 7% |
| Student > Postgraduate | 5 | 6% |
| Other | 6 | 7% |
| Unknown | 23 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 23 | 27% |
| Psychology | 11 | 13% |
| Medicine and Dentistry | 6 | 7% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Engineering | 3 | 3% |
| Other | 12 | 14% |
| Unknown | 28 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2018.
All research outputs
#14,427,897
of 24,217,893 outputs
Outputs from Brain Structure and Function
#773
of 1,725 outputs
Outputs of similar age
#228,934
of 450,417 outputs
Outputs of similar age from Brain Structure and Function
#13
of 43 outputs
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