| Title |
Reassessing the Evidence Hierarchy in Asthma: Evaluating Comparative Effectiveness
|
|---|---|
| Published in |
Current Allergy and Asthma Reports, September 2011
|
| DOI | 10.1007/s11882-011-0222-7 |
| Pubmed ID | |
| Authors |
David Price, Alison Chisholm, Thys van der Molen, Nicolas Roche, Elizabeth V. Hillyer, Jean Bousquet |
| Abstract |
Classical randomized controlled trials are the gold standard in medical evidence because of their high internal validity. However, their necessarily strict design can limit their external validity and the ability to extrapolate these data to real world patients. Therefore, alternatively designed studies may play a complementary role in evaluating the comparative effectiveness of therapies in nonidealized patients in more naturalistic, real world settings. Observational studies have high external validity and can evaluate real world outcomes. Their strength lies in hypothesis generation and testing and in identifying areas in which further clinical trials may be required. Pragmatic trials are designed to maximize applicability of trial results to usual care settings by relying on clinically important outcomes and enrolling a wide range of participants. A combination of these approaches is preferable and necessary. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Tunisia | 1 | 2% |
| Unknown | 50 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 11 | 21% |
| Researcher | 9 | 17% |
| Student > Master | 8 | 15% |
| Professor > Associate Professor | 3 | 6% |
| Professor | 3 | 6% |
| Other | 7 | 13% |
| Unknown | 11 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 40% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 13% |
| Nursing and Health Professions | 4 | 8% |
| Economics, Econometrics and Finance | 3 | 6% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 12 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2011.
All research outputs
#18,295,723
of 22,651,245 outputs
Outputs from Current Allergy and Asthma Reports
#651
of 802 outputs
Outputs of similar age
#108,214
of 130,159 outputs
Outputs of similar age from Current Allergy and Asthma Reports
#6
of 7 outputs
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So far Altmetric has tracked 802 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
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