| Title |
Neuropsychological and Behavioral Effects of Antiepilepsy Drugs
|
|---|---|
| Published in |
Neuropsychology Review, October 2007
|
| DOI | 10.1007/s11065-007-9043-9 |
| Pubmed ID | |
| Authors |
David W. Loring, Susan Marino, Kimford J. Meador |
| Abstract |
Antiepilepsy drugs work by decreasing neuronal irritability, which may also result in the non-desired side effect of decreased neuropsychological function. In addition to cognitive side effects, antiepilepsy drugs (AEDs) may be associated with behavioral effects which may range from irritability and hyperactivity to positive psychotropic effects on mood. There have been many new medications released since the 1990s, and although they tend to have more favorable side effect profiles compared to their older counterparts, there continues to be a risk of decreased cognitive function with the majority of these agents. The effects of in utero antiepilepsy drug exposure are increasingly being investigated, and differential drug risk is beginning to be described for both anatomic and cognitive outcomes. Patients with epilepsy undergoing neuropsychological evaluations are commonly on AEDs, and it is important for the clinician to recognize the potential contribution of AED therapy to neuropsychological profiles. The present article serves to provide an overview of our current understanding regarding the risks of antiepilepsy drug use for both cognitive and behavioral side effects. |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Mexico | 1 | <1% |
| France | 1 | <1% |
| Unknown | 132 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 18% |
| Student > Ph. D. Student | 21 | 15% |
| Student > Master | 13 | 9% |
| Student > Doctoral Student | 10 | 7% |
| Other | 10 | 7% |
| Other | 30 | 22% |
| Unknown | 28 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 41 | 30% |
| Medicine and Dentistry | 35 | 26% |
| Agricultural and Biological Sciences | 8 | 6% |
| Neuroscience | 4 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 11 | 8% |
| Unknown | 34 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2022.
All research outputs
#2,920,328
of 22,675,759 outputs
Outputs from Neuropsychology Review
#109
of 450 outputs
Outputs of similar age
#7,463
of 75,414 outputs
Outputs of similar age from Neuropsychology Review
#3
of 4 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 450 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 75,414 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.