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Mendeley readers
| Title |
Yeast as a model for studying Alzheimer's disease
|
|---|---|
| Published in |
FEMS Yeast Research, November 2010
|
| DOI | 10.1111/j.1567-1364.2010.00658.x |
| Pubmed ID | |
| Authors |
Prashant Bharadwaj, Ralph Martins, Ian Macreadie |
| Abstract |
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by acute cognitive decline. The AD brain is featured by extracellular senile amyloid plaques, intraneuronal neurofibrillary tangles and extensive neuronal cell loss in specific regions of the brain associated with memory. The exact mechanism of neuronal cell dysfunction leading to the memory loss in AD is poorly understood. A number of studies have indicated that yeast is a suitable model system to decipher the molecular mechanisms involved in a variety of neurodegenerative disorders caused by pathological protein misfolding and deposition. Here, the knowledge from various studies that have utilized a yeast model to study the mechanism of pathways involved in AD pathogenesis is summarized. |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | <1% |
| Sweden | 1 | <1% |
| Canada | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 127 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 20% |
| Student > Master | 27 | 20% |
| Student > Bachelor | 25 | 19% |
| Student > Ph. D. Student | 18 | 14% |
| Student > Doctoral Student | 7 | 5% |
| Other | 16 | 12% |
| Unknown | 12 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 35% |
| Biochemistry, Genetics and Molecular Biology | 34 | 26% |
| Medicine and Dentistry | 8 | 6% |
| Physics and Astronomy | 5 | 4% |
| Chemistry | 4 | 3% |
| Other | 17 | 13% |
| Unknown | 18 | 14% |