Title |
Bupropion Versus Sertraline in the Treatment of Depressive Patients with Binge Eating Disorder: Retrospective Cohort Study
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Published in |
Psychiatric Quarterly, September 2011
|
DOI | 10.1007/s11126-011-9192-0 |
Pubmed ID | |
Authors |
Carmela Calandra, Rina Giuseppa Russo, Maria Luca |
Abstract |
This study sought to compare Bupropion versus Sertraline in the treatment of depressed patients with Binge Eating Disorder (BED) prescribed off-label. Medical records of outpatients with diagnosis of BED and Depression (DSM-IV-TR criteria) were selected: 15 patients were treated with bupropion 150 mg/per day, and 15 with sertraline 200 mg/per day. During the screening and control visits (2°-6°-14°-24° week), the selected patients were first weighed and then evaluated using the following questionnaires: Binge Eating Disorder-Clinical Interview (BEDCI), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory X (STAI-X) and Arizona Sexual Experience Scale (ASEX). Both drugs reduced anxious-depressive symptoms and binge frequency: Bupropion showed a better effectiveness in reducing weight and improving sexual performances; weight loss related to it was proportional to the body mass index. Bupropion may be associated with more weight loss in BED, depressed patients than sertraline. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 3 | 3% |
Unknown | 84 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 17% |
Student > Bachelor | 15 | 17% |
Student > Ph. D. Student | 9 | 10% |
Student > Master | 9 | 10% |
Other | 8 | 9% |
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Unknown | 14 | 16% |
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Psychology | 20 | 23% |
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Agricultural and Biological Sciences | 3 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 8 | 9% |
Unknown | 19 | 22% |