| Title |
Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors
|
|---|---|
| Published in |
Cell Biology and Toxicology, January 2000
|
| DOI | 10.1023/a:1007685909018 |
| Pubmed ID | |
| Authors |
A. Russo, R. Acquaviva, A. Campisi, V. Sorrenti, C. Di Giacomo, G. Virgata, M.L. Barcellona, A. Vanella |
| Abstract |
Flavonoids have recently aroused considerable interest because of their broad pharmacological activity. In fact, flavonoids have been reported to have antiviral, antiallergic, antiplatelet, anti-inflammatory and antitumoral activities. The pharmacological properties of bioflavonoids have been ascribed both to the concomitant inhibition of enzymes involved in the production of free radicals and to their free-radical scavenging and iron chelating capacity. However the antioxidant capacity of bioflavonoids due to free-radical scavenging and/or to iron chelating is still controversial. In this study, we have investigated the free-radical scavenging capacity of bioflavonoids (rutin, catechin, and naringin). In addition, the effects of these polyphenols on xanthine oxidase activity, spontaneous lipid peroxidation, and DNA cleavage were investigated. The bioflavonoids under examination showed a dose-dependent free-radical scavenging effect, a significant inhibition of xanthine oxidase activity, and an antilipoperoxidative capacity. In addition, they showed a protective effect on DNA cleavage. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Bangladesh | 1 | <1% |
| Unknown | 110 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 12% |
| Researcher | 12 | 11% |
| Student > Bachelor | 11 | 10% |
| Student > Doctoral Student | 9 | 8% |
| Student > Postgraduate | 8 | 7% |
| Other | 21 | 19% |
| Unknown | 37 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 12% |
| Biochemistry, Genetics and Molecular Biology | 11 | 10% |
| Chemistry | 9 | 8% |
| Nursing and Health Professions | 4 | 4% |
| Other | 10 | 9% |
| Unknown | 43 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2020.
All research outputs
#2,063,061
of 25,374,647 outputs
Outputs from Cell Biology and Toxicology
#12
of 525 outputs
Outputs of similar age
#2,743
of 109,784 outputs
Outputs of similar age from Cell Biology and Toxicology
#1
of 4 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 525 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,784 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them