Title |
Pregnancy After Tubal Sterilization in a Woman Treated with Biologics for Severe Psoriasis
|
---|---|
Published in |
Dermatology and Therapy, March 2018
|
DOI | 10.1007/s13555-018-0232-7 |
Pubmed ID | |
Authors |
Charlée Nardin, Morgane Colas, Vincent Curie, Fabien Pelletier, Eve Puzenat, François Aubin |
Abstract |
Little is known about whether immunosuppressed patients mount the immunological response necessary to ensure tubal occlusion. Theoretical concern for non-occlusion has limited the use of hysteroscopic sterilization in patients on immunosuppressive therapies. The effects of tumor necrosis factor-alpha (TNF-α) blockers and interleukin (IL)-17 inhibitors on contraception and pregnancy for patients with psoriasis are poorly documented. We report a case of pregnancy that ended in miscarriage in a patient treated first with TNF-α and then with IL-17 inhibitors for severe psoriasis after tubal sterilization with micro-inserts. Our observation suggests that the efficacy of tubal sterilization by micro-inserts may be impaired by these two biologics and that the risk of miscarriage may be increased in women with psoriasis treated with secukinumab. |
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United Kingdom | 1 | 100% |
Demographic breakdown
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 6 | 29% |
Other | 3 | 14% |
Unspecified | 2 | 10% |
Student > Ph. D. Student | 2 | 10% |
Student > Doctoral Student | 1 | 5% |
Other | 1 | 5% |
Unknown | 6 | 29% |
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Unspecified | 2 | 10% |
Social Sciences | 2 | 10% |
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Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Other | 2 | 10% |
Unknown | 6 | 29% |