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Fetal Endothelial and Mesenchymal Progenitors From the Human Term Placenta: Potency and Clinical Potential

Overview of attention for article published in Stem Cells Translational Medicine, March 2015
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2 Facebook pages

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34 Mendeley
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Title
Fetal Endothelial and Mesenchymal Progenitors From the Human Term Placenta: Potency and Clinical Potential
Published in
Stem Cells Translational Medicine, March 2015
DOI 10.5966/sctm.2014-0224
Pubmed ID
Authors

Abbas Shafiee, Nicholas M. Fisk, Dietmar W. Hutmacher, Kiarash Khosrotehrani, Jatin Patel

Abstract

SummarySince the isolation of fetal stem cell populations from perinatal tissues, such as umbilical cord blood and placenta, interest has been growing in understanding their greater plasticity compared with adult stem cells and exploring their potential in regenerative medicine. The phenomenon of fetal microchimerism (FMC) naturally occurring during pregnancy through the transfer of fetal stem/progenitor cells to maternal blood and tissues has been integral in developing this dogma. Specifically, microchimeric mesenchymal stem cells and endothelial progenitors of fetal origin have now demonstrated a capacity for tissue repair in the maternal host. However, the use of similar fetal stem cells in therapy has been significantly hampered by the availability of clinically relevant cell numbers and/or contamination with cells of maternal origin, particularly when using the chorionic and decidual placenta. In the present prospective review, we highlight the importance of FMC to the field of fetal stem cell biology and issues of maternal contamination from perinatal tissues and discuss specific isolation strategies to overcome these translational obstacles.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Master 6 18%
Student > Bachelor 4 12%
Student > Ph. D. Student 4 12%
Student > Postgraduate 4 12%
Other 4 12%
Unknown 4 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 26%
Medicine and Dentistry 6 18%
Biochemistry, Genetics and Molecular Biology 6 18%
Engineering 2 6%
Arts and Humanities 1 3%
Other 2 6%
Unknown 8 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2016.
All research outputs
#13,937,513
of 22,794,367 outputs
Outputs from Stem Cells Translational Medicine
#1,038
of 1,517 outputs
Outputs of similar age
#132,830
of 260,871 outputs
Outputs of similar age from Stem Cells Translational Medicine
#29
of 46 outputs
Altmetric has tracked 22,794,367 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.5. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.