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Ginsenosides potentiate P2X7 receptors

Overview of attention for article published in British Journal of Pharmacology, April 2015
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3 X users

Citations

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39 Dimensions

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24 Mendeley
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Title
Ginsenosides potentiate P2X7 receptors
Published in
British Journal of Pharmacology, April 2015
DOI 10.1111/bph.13123
Pubmed ID
Authors

R M Helliwell, C O ShioukHuey, K Dhuna, J C Molero, J-M Ye, C C Xue, L Stokes

Abstract

P2X7 is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes. Ginseng is a well-known Chinese herb with both pro- and anti-inflammatory properties where many of these actions have been ascribed to constituent ginsenosides. We performed a screen to determine if ginsenoside compounds could display pharmacological activity at P2X7 that might contribute to the reported immunomodulatory actions of ginseng.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Lecturer > Senior Lecturer 2 8%
Student > Doctoral Student 2 8%
Student > Bachelor 2 8%
Student > Ph. D. Student 2 8%
Other 2 8%
Unknown 9 38%
Readers by discipline Count As %
Medicine and Dentistry 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Agricultural and Biological Sciences 2 8%
Neuroscience 2 8%
Immunology and Microbiology 2 8%
Other 3 13%
Unknown 10 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2015.
All research outputs
#14,887,818
of 24,417,958 outputs
Outputs from British Journal of Pharmacology
#5,817
of 7,563 outputs
Outputs of similar age
#137,218
of 269,458 outputs
Outputs of similar age from British Journal of Pharmacology
#49
of 88 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,563 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,458 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.