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Mendeley readers
Attention Score in Context
| Title |
Inhibition of α-amylase activity by cellulose: Kinetic analysis and nutritional implications
|
|---|---|
| Published in |
Carbohydrate Polymers, February 2015
|
| DOI | 10.1016/j.carbpol.2015.01.039 |
| Pubmed ID | |
| Authors |
Sushil Dhital, Michael J. Gidley, Frederick J. Warren |
| Abstract |
We report on inhibition of α-amylase activity by cellulose based on in vitro experiments. The presence of cellulose in the hydrolysing medium reduced the initial velocity of starch hydrolysis in a concentration dependent manner. α-Amylase adsorption to cellulose was reversible, attaining equilibrium within 30min of incubation, and showed a higher affinity at 37°C compared to 20 and 0°C. The adsorption was almost unchanged in the presence of maltose (2.5-20mM) but was hindered in the presence of excess protein, suggesting non-specific adsorption of α-amylase to cellulose. Kinetic analyses of α-amylase hydrolysis of maize starch in the presence of cellulose showed that the inhibition is of a mixed type. The dissociation constant (Kic) of the EI complex was found to be ca. 3mg/mL. The observed inhibition of α-amylase activity suggests that cellulose in the diet can potentially attenuate starch hydrolysis. |
Mendeley readers
The data shown below were compiled from readership statistics for 172 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 170 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 21% |
| Student > Bachelor | 21 | 12% |
| Student > Master | 19 | 11% |
| Researcher | 18 | 10% |
| Student > Doctoral Student | 10 | 6% |
| Other | 19 | 11% |
| Unknown | 49 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 44 | 26% |
| Chemistry | 15 | 9% |
| Biochemistry, Genetics and Molecular Biology | 10 | 6% |
| Engineering | 7 | 4% |
| Immunology and Microbiology | 5 | 3% |
| Other | 25 | 15% |
| Unknown | 66 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2015.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Carbohydrate Polymers
#4,341
of 5,157 outputs
Outputs of similar age
#308,569
of 360,368 outputs
Outputs of similar age from Carbohydrate Polymers
#56
of 78 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,157 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,368 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.