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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Multilineage Priming of Enhancer Repertoires Precedes Commitment to the B and Myeloid Cell Lineages in Hematopoietic Progenitors
|
|---|---|
| Published in |
Immunity, September 2011
|
| DOI | 10.1016/j.immuni.2011.06.013 |
| Pubmed ID | |
| Authors |
Elinore M. Mercer, Yin C. Lin, Christopher Benner, Suchit Jhunjhunwala, Janusz Dutkowski, Martha Flores, Mikael Sigvardsson, Trey Ideker, Christopher K. Glass, Cornelis Murre |
| Abstract |
Recent studies have documented genome-wide binding patterns of transcriptional regulators and their associated epigenetic marks in hematopoietic cell lineages. In order to determine how epigenetic marks are established and maintained during developmental progression, we have generated long-term cultures of hematopoietic progenitors by enforcing the expression of the E-protein antagonist Id2. Hematopoietic progenitors that express Id2 are multipotent and readily differentiate upon withdrawal of Id2 expression into committed B lineage cells, thus indicating a causative role for E2A (Tcf3) in promoting the B cell fate. Genome-wide analyses revealed that a substantial fraction of lymphoid and myeloid enhancers are premarked by the poised or active enhancer mark H3K4me1 in multipotent progenitors. Thus, in hematopoietic progenitors, multilineage priming of enhancer elements precedes commitment to the lymphoid or myeloid cell lineages. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 3% |
| Germany | 1 | <1% |
| France | 1 | <1% |
| Italy | 1 | <1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| Denmark | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 143 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 35% |
| Researcher | 36 | 23% |
| Student > Bachelor | 11 | 7% |
| Professor | 9 | 6% |
| Student > Master | 9 | 6% |
| Other | 20 | 13% |
| Unknown | 15 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 69 | 45% |
| Biochemistry, Genetics and Molecular Biology | 44 | 28% |
| Immunology and Microbiology | 9 | 6% |
| Medicine and Dentistry | 7 | 5% |
| Computer Science | 1 | <1% |
| Other | 9 | 6% |
| Unknown | 16 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2023.
All research outputs
#3,799,086
of 25,374,917 outputs
Outputs from Immunity
#2,245
of 4,816 outputs
Outputs of similar age
#19,398
of 136,351 outputs
Outputs of similar age from Immunity
#12
of 44 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,816 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 33.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 136,351 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.