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A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes

Overview of attention for article published in Molecular & Biochemical Parasitology, September 2011
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Title
A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes
Published in
Molecular & Biochemical Parasitology, September 2011
DOI 10.1016/j.molbiopara.2011.09.002
Pubmed ID
Authors

Christopher L. Peatey, Timothy P. Spicer, Peter S. Hodder, Katharine R. Trenholme, Donald L. Gardiner

Abstract

Recent success in the global reduction campaign against malaria has resulted in the possibility that it may be feasible to drastically reduce or even eradicate malaria even without the introduction of a vaccine. However, while there has been significant effort to design the next generation of antimalarial drugs, one area that is underrepresented in the current antimalarial pharmacopeia is that of transmission blocking drugs directed at late-stage gametocytes. Here we describe the development of a robust and simple assay that is amenable to a high throughput format for the discovery of new antigametocyte drugs.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Pakistan 1 2%
Germany 1 2%
Unknown 62 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 23%
Researcher 12 18%
Student > Master 9 14%
Other 6 9%
Student > Bachelor 3 5%
Other 12 18%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 32%
Biochemistry, Genetics and Molecular Biology 13 20%
Chemistry 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Medicine and Dentistry 4 6%
Other 6 9%
Unknown 8 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2011.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Molecular & Biochemical Parasitology
#1,505
of 1,713 outputs
Outputs of similar age
#108,760
of 129,987 outputs
Outputs of similar age from Molecular & Biochemical Parasitology
#9
of 11 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,713 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,987 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.