| Title |
Forkhead box O1 mediates defects in palmitate-induced insulin granule exocytosis by downregulation of calcium/calmodulin-dependent serine protein kinase expression in INS-1 cells
|
|---|---|
| Published in |
Diabetologia, March 2015
|
| DOI | 10.1007/s00125-015-3561-4 |
| Pubmed ID | |
| Authors |
Yao Wang, Haiyan Lin, Nana Hao, Zhengqiu Zhu, Dong Wang, Yuan Li, Hong Chen, Yunxia Zhu, Xiao Han |
| Abstract |
The transcription factor forkhead box O1 (FOXO1) induces pancreatic islet beta cell endoplasmic reticulum stress and is involved in fatty-acid-induced insulin-secretion defects. Cask is a downstream target gene of FOXO1. Using INS-1 cells with palmitate-induced insulin-release defects, we investigated the relationship between FOXO1 and Cask. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 30% |
| Professor | 2 | 20% |
| Researcher | 2 | 20% |
| Student > Master | 1 | 10% |
| Other | 1 | 10% |
| Other | 0 | 0% |
| Unknown | 1 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
| Biochemistry, Genetics and Molecular Biology | 1 | 10% |
| Psychology | 1 | 10% |
| Medicine and Dentistry | 1 | 10% |
| Other | 1 | 10% |
| Unknown | 3 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2015.
All research outputs
#20,265,771
of 22,796,179 outputs
Outputs from Diabetologia
#4,880
of 5,035 outputs
Outputs of similar age
#222,594
of 262,879 outputs
Outputs of similar age from Diabetologia
#64
of 66 outputs
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We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.