| Title |
Histone deacetylase activity is necessary for left-right patterning during vertebrate development
|
|---|---|
| Published in |
BMC Developmental Biology, May 2011
|
| DOI | 10.1186/1471-213x-11-29 |
| Pubmed ID | |
| Authors |
Katia Carneiro, Claudia Donnet, Tomas Rejtar, Barry L Karger, Gustavo A Barisone, Elva Díaz, Sandhya Kortagere, Joan M Lemire, Michael Levin |
| Abstract |
Consistent asymmetry of the left-right (LR) axis is a crucial aspect of vertebrate embryogenesis. Asymmetric gene expression of the TGFβ superfamily member Nodal related 1 (Nr1) in the left lateral mesoderm plate is a highly conserved step regulating the situs of the heart and viscera. In Xenopus, movement of maternal serotonin (5HT) through gap-junctional paths at cleavage stages dictates asymmetry upstream of Nr1. However, the mechanisms linking earlier biophysical asymmetries with this transcriptional control point are not known. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 5% |
| Mexico | 1 | 1% |
| Germany | 1 | 1% |
| Argentina | 1 | 1% |
| Unknown | 71 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 31% |
| Researcher | 13 | 17% |
| Student > Bachelor | 11 | 14% |
| Student > Master | 8 | 10% |
| Student > Doctoral Student | 6 | 8% |
| Other | 12 | 15% |
| Unknown | 4 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 46% |
| Biochemistry, Genetics and Molecular Biology | 18 | 23% |
| Medicine and Dentistry | 5 | 6% |
| Neuroscience | 3 | 4% |
| Arts and Humanities | 2 | 3% |
| Other | 11 | 14% |
| Unknown | 3 | 4% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2022.
All research outputs
#12,848,572
of 22,653,392 outputs
Outputs from BMC Developmental Biology
#196
of 369 outputs
Outputs of similar age
#77,159
of 111,490 outputs
Outputs of similar age from BMC Developmental Biology
#4
of 7 outputs
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So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
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