| Title |
Serious haematological toxicity during and after ipilimumab treatment: a case series
|
|---|---|
| Published in |
Journal of Medical Case Reports, July 2014
|
| DOI | 10.1186/1752-1947-8-240 |
| Pubmed ID | |
| Authors |
Ester Simeone, Antonio Maria Grimaldi, Assunta Esposito, Marcello Curvietto, Marco Palla, Miriam Paone, Nicola Mozzillo, Paolo Antonio Ascierto |
| Abstract |
Immunotherapy with the anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody ipilimumab has been shown to improve overall survival in previously treated and treatment-naïve patients with unresectable stage III or IV melanoma. Consistent with its proposed immunomodulating mechanism of action, the most common toxicities associated with ipilimumab therapy are immune-related in nature and include those related to the skin and gastrointestinal tract, with endocrine and hepatic events also frequent. Other rare adverse events, including haematological aberrations, may also occur and can have serious consequences if unrecognised. Here we describe three patients who developed serious haematological adverse events during or after treatment with ipilimumab. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 2% |
| Unknown | 55 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 13% |
| Student > Ph. D. Student | 7 | 13% |
| Researcher | 6 | 11% |
| Other | 6 | 11% |
| Student > Doctoral Student | 4 | 7% |
| Other | 10 | 18% |
| Unknown | 16 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 45% |
| Agricultural and Biological Sciences | 3 | 5% |
| Nursing and Health Professions | 2 | 4% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Neuroscience | 2 | 4% |
| Other | 2 | 4% |
| Unknown | 20 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2018.
All research outputs
#18,403,994
of 22,796,179 outputs
Outputs from Journal of Medical Case Reports
#2,258
of 3,915 outputs
Outputs of similar age
#163,329
of 227,632 outputs
Outputs of similar age from Journal of Medical Case Reports
#36
of 54 outputs
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