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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exome sequencing as a tool for Mendelian disease gene discovery
|
|---|---|
| Published in |
Nature Reviews Genetics, September 2011
|
| DOI | 10.1038/nrg3031 |
| Pubmed ID | |
| Authors |
Michael J. Bamshad, Sarah B. Ng, Abigail W. Bigham, Holly K. Tabor, Mary J. Emond, Deborah A. Nickerson, Jay Shendure |
| Abstract |
Exome sequencing - the targeted sequencing of the subset of the human genome that is protein coding - is a powerful and cost-effective new tool for dissecting the genetic basis of diseases and traits that have proved to be intractable to conventional gene-discovery strategies. Over the past 2 years, experimental and analytical approaches relating to exome sequencing have established a rich framework for discovering the genes underlying unsolved Mendelian disorders. Additionally, exome sequencing is being adapted to explore the extent to which rare alleles explain the heritability of complex diseases and health-related traits. These advances also set the stage for applying exome and whole-genome sequencing to facilitate clinical diagnosis and personalized disease-risk profiling. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 6% |
| Japan | 1 | 6% |
| Spain | 1 | 6% |
| United States | 1 | 6% |
| Unknown | 14 | 78% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 94% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 2,338 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 39 | 2% |
| United Kingdom | 16 | <1% |
| Germany | 13 | <1% |
| Brazil | 9 | <1% |
| Korea, Republic of | 6 | <1% |
| Canada | 6 | <1% |
| Spain | 5 | <1% |
| India | 5 | <1% |
| Italy | 5 | <1% |
| Other | 50 | 2% |
| Unknown | 2184 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 536 | 23% |
| Researcher | 450 | 19% |
| Student > Master | 310 | 13% |
| Student > Bachelor | 241 | 10% |
| Student > Postgraduate | 117 | 5% |
| Other | 433 | 19% |
| Unknown | 251 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 892 | 38% |
| Biochemistry, Genetics and Molecular Biology | 500 | 21% |
| Medicine and Dentistry | 362 | 15% |
| Computer Science | 81 | 3% |
| Neuroscience | 47 | 2% |
| Other | 164 | 7% |
| Unknown | 292 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#878,187
of 25,837,817 outputs
Outputs from Nature Reviews Genetics
#470
of 2,745 outputs
Outputs of similar age
#3,456
of 144,787 outputs
Outputs of similar age from Nature Reviews Genetics
#3
of 40 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,745 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 32.6. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,787 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.