| Title |
NGAL: a biomarker of acute kidney injury and other systemic conditions
|
|---|---|
| Published in |
Geriatric Nephrology and Urology, July 2009
|
| DOI | 10.1007/s11255-009-9608-z |
| Pubmed ID | |
| Authors |
Sachin S. Soni, Dinna Cruz, Ilona Bobek, Chang Yin Chionh, Federico Nalesso, Paolo Lentini, Massimo de Cal, Valentina Corradi, Grazia Virzi, Claudio Ronco |
| Abstract |
Neutrophil gelatinase-associated lipocalin (NGAL) is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells, like kidney tubular cells, may produce NGAL in response to various insults. Recently, it has been found to have a role in iron metabolism by virtue of its binding with siderophores. It has also been found to have a role in kidney development and tubular regeneration after injury. In experimental studies, it was found to be highly expressed in response to tubular injury. In subsequent clinical studies, urine NGAL has been found to be an early predictor for acute kidney injury (AKI). Newer devices for early bedside detection of NGAL are now available. Since serum creatinine is known to be an inadequate and late marker of AKI, NGAL might soon emerge as a troponin-like early marker for AKI. Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | <1% |
| Norway | 1 | <1% |
| Argentina | 1 | <1% |
| Unknown | 192 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 11% |
| Researcher | 19 | 10% |
| Student > Bachelor | 16 | 8% |
| Student > Doctoral Student | 15 | 8% |
| Student > Master | 15 | 8% |
| Other | 50 | 26% |
| Unknown | 59 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 71 | 36% |
| Agricultural and Biological Sciences | 16 | 8% |
| Biochemistry, Genetics and Molecular Biology | 15 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 4% |
| Veterinary Science and Veterinary Medicine | 4 | 2% |
| Other | 14 | 7% |
| Unknown | 67 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2015.
All research outputs
#7,960,693
of 25,374,917 outputs
Outputs from Geriatric Nephrology and Urology
#377
of 1,493 outputs
Outputs of similar age
#39,572
of 121,712 outputs
Outputs of similar age from Geriatric Nephrology and Urology
#2
of 5 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,493 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,712 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.