| Title |
Body mass index and the risk of rheumatoid arthritis: a systematic review and dose-response meta-analysis
|
|---|---|
| Published in |
Arthritis Research & Therapy, March 2015
|
| DOI | 10.1186/s13075-015-0601-x |
| Pubmed ID | |
| Authors |
Baodong Qin, Min Yang, Haitao Fu, Ning Ma, Tingting Wei, Qingqin Tang, Zhide Hu, Yan Liang, Zaixing Yang, Renqian Zhong |
| Abstract |
The evidence from published studies on the association between obesity and rheumatoid arthritis (RA) has been contradictory. To clarify the association between obesity and RA, we conducted a systematic review and dose-response meta-analysis to assess the relationship between body mass index (BMI) and RA risk. A systematic literature search of Pubmed and Embase (up to July 12, 2014) was performed to identify all eligible published reports. The pooled relative risk (RR) results with corresponding 95% confidence intervals (CIs) of RA development were estimated using a random effects model. Eleven eligible related citations fulfilled the inclusion criteria and were included in the study. Compared with individuals with BMI < 30, obese individuals showed an association with a significantly increased risk of RA (RR = 1.25, 95%CI 1.07-1.45, Pheterogeneity < 0.01, I(2) = 63%). Compared to normal weight subjects, the pooled RRs for RA were 1.31 (1.12-1.53) and 1.15 (1.03-1.29) for the categories of obese and overweight, respectively. In the dose-response analysis, there was evidence of a nonlinear association (Pnon-linear =0.005) and the estimated summary RR for a 5-unit increment was 1.03 (95%CI 1.01-1.05, Pheterogeneity = 0.001, I(2) = 70.0%). An increase in BMI can contribute to a higher risk for RA development. However, the finding also highlights the need for research on the association between BMI and RA risk with adjustment for more confounding factors. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Colombia | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Scientists | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 217 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Unknown | 216 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 35 | 16% |
| Student > Master | 28 | 13% |
| Student > Ph. D. Student | 23 | 11% |
| Researcher | 19 | 9% |
| Student > Postgraduate | 13 | 6% |
| Other | 34 | 16% |
| Unknown | 65 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 68 | 31% |
| Nursing and Health Professions | 17 | 8% |
| Biochemistry, Genetics and Molecular Biology | 13 | 6% |
| Immunology and Microbiology | 13 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 6% |
| Other | 18 | 8% |
| Unknown | 76 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2023.
All research outputs
#2,695,939
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#542
of 3,381 outputs
Outputs of similar age
#33,829
of 278,244 outputs
Outputs of similar age from Arthritis Research & Therapy
#9
of 75 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,244 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.