| Title |
Are non-steroidal anti-inflammatory drugs effective for the management of neck pain and associated disorders, whiplash-associated disorders, or non-specific low back pain? A systematic review of systematic reviews by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration
|
|---|---|
| Published in |
European Spine Journal, April 2015
|
| DOI | 10.1007/s00586-015-3891-4 |
| Pubmed ID | |
| Authors |
Jessica J. Wong, Pierre Côté, Arthur Ameis, Sharanya Varatharajan, Thepikaa Varatharajan, Heather M. Shearer, Robert J. Brison, Deborah Sutton, Kristi Randhawa, Hainan Yu, Danielle Southerst, Rachel Goldgrub, Silvano Mior, Maja Stupar, Linda J. Carroll, Anne Taylor-Vaisey |
| Abstract |
To evaluate the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for the management of neck pain and associated disorders (NAD), whiplash-associated disorders, and non-specific low back pain (LBP) with or without radiculopathy. We systematically searched six databases from 2000 to 2014. Random pairs of independent reviewers critically appraised eligible systematic reviews using the Scottish Intercollegiate Guidelines Network criteria. We included systematic reviews with a low risk of bias in our best evidence synthesis. We screened 706 citations and 14 systematic reviews were eligible for critical appraisal. Eight systematic reviews had a low risk of bias. For recent-onset NAD, evidence suggests that intramuscular NSAIDs lead to similar outcomes as combined manipulation and soft tissue therapy. For NAD (duration not specified), oral NSAIDs may be more effective than placebo. For recent-onset LBP, evidence suggests that: (1) oral NSAIDs lead to similar outcomes to placebo or a muscle relaxant; and (2) oral NSAIDs with bed rest lead to similar outcomes as placebo with bed rest. For persistent LBP, evidence suggests that: (1) oral NSAIDs are more effective than placebo; and (2) oral NSAIDs may be more effective than acetaminophen. For recent-onset LBP with radiculopathy, there is inconsistent evidence on the effectiveness of oral NSAIDs versus placebo. Finally, different oral NSAIDs lead to similar outcomes for neck and LBP with or without radiculopathy. For NAD, oral NSAIDs may be more effective than placebo. Oral NSAIDs are more effective than placebo for persistent LBP, but not for recent-onset LBP. Different oral NSAIDs lead to similar outcomes for neck pain and LBP. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 57% |
| Malaysia | 1 | 7% |
| Unknown | 5 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 43% |
| Practitioners (doctors, other healthcare professionals) | 5 | 36% |
| Scientists | 2 | 14% |
| Unknown | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Lebanon | 1 | <1% |
| Unknown | 129 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 14% |
| Student > Master | 15 | 11% |
| Student > Doctoral Student | 14 | 11% |
| Student > Ph. D. Student | 13 | 10% |
| Student > Bachelor | 12 | 9% |
| Other | 25 | 19% |
| Unknown | 35 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 34 | 26% |
| Nursing and Health Professions | 28 | 21% |
| Sports and Recreations | 5 | 4% |
| Social Sciences | 5 | 4% |
| Psychology | 4 | 3% |
| Other | 11 | 8% |
| Unknown | 45 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2023.
All research outputs
#2,250,313
of 24,126,099 outputs
Outputs from European Spine Journal
#198
of 4,965 outputs
Outputs of similar age
#29,394
of 268,641 outputs
Outputs of similar age from European Spine Journal
#6
of 165 outputs
Altmetric has tracked 24,126,099 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,965 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done particularly well, scoring higher than 96% of its peers.
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We're also able to compare this research output to 165 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.