| Title |
Health-related quality of life following pediatric critical illness
|
|---|---|
| Published in |
Intensive Care Medicine, April 2015
|
| DOI | 10.1007/s00134-015-3780-7 |
| Pubmed ID | |
| Authors |
François Aspesberro, Rita Mangione-Smith, Jerry J. Zimmerman |
| Abstract |
The aims of this focused review of the literature on children surviving critical illness were to (1) determine whether health-related quality of life (HRQL) represents a clinically meaningful outcome measure for children surviving critical illness and (2) evaluate the HRQL measures implemented in pediatric critical care studies to date. This was a focused review of the literature from 1980 to 2015 based on a search of EMBASE/PubMed, MEDLINE and PsycInfo assessing trends and determinants of HRQL outcomes in children surviving critical illness. We also evaluated the psychometric properties of the HRQL instruments used in the studies identified by examining each measure's reported reliability, validity and sensitivity to clinical change. The literature search identified 253 pediatric articles for potential inclusion in the review, among which data from 78 studies were ultimately selected for inclusion. Of the 22 measures utilized in the studies reviewed, only four demonstrated excellent psychometric properties for use in pediatric critical care trials. Trends in HRQL identified in the studies reviewed suggest significant ongoing morbidity for children surviving critical illness. Key determinants of poor HRQL outcomes include reason for PICU admission (sepsis, meningoencephalitis, trauma), antecedents (chronic comorbid conditions), treatments received (prolonged cardiopulmonary resuscitation, long-stay patients, invasive technology), psychological outcomes (post-traumatic stress disorder, parent anxiety/depression) and social and environmental characteristics (low socioeconomic status, parental education and functioning). Validated pediatric HRQL instruments are now available. Significant impact on HRQL has been demonstrated in acute and acute on chronic critical illness. Future pediatric critical care interventional trials should include both mortality as well as long-term HRQL measurements to truly ascertain the full impact of critical illness in children. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| India | 1 | 33% |
| United Kingdom | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Unknown | 170 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 26 | 15% |
| Researcher | 18 | 11% |
| Student > Postgraduate | 18 | 11% |
| Student > Bachelor | 18 | 11% |
| Student > Ph. D. Student | 14 | 8% |
| Other | 40 | 23% |
| Unknown | 37 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 66 | 39% |
| Nursing and Health Professions | 27 | 16% |
| Psychology | 15 | 9% |
| Social Sciences | 6 | 4% |
| Neuroscience | 2 | 1% |
| Other | 15 | 9% |
| Unknown | 40 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2015.
All research outputs
#14,220,809
of 22,797,621 outputs
Outputs from Intensive Care Medicine
#3,824
of 4,977 outputs
Outputs of similar age
#139,716
of 264,934 outputs
Outputs of similar age from Intensive Care Medicine
#46
of 94 outputs
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