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The impact of photobiomodulation on osteoblast-like cell: a review

Overview of attention for article published in Lasers in Medical Science, March 2018
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Title
The impact of photobiomodulation on osteoblast-like cell: a review
Published in
Lasers in Medical Science, March 2018
DOI 10.1007/s10103-018-2486-9
Pubmed ID
Authors

Alessandro Melo Deana, Ana Maria de Souza, Victor Perez Teixeira, Raquel Agneli Mesquita-Ferrari, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes

Abstract

In this study, we present a review of the literature on the impact of photobiomodulation on osteoblast-like cell culture. Searches were performed in the PubMed/MEDLINE (Medical Literature Analysis and Retrieval System Online), SCOPUS, and SPIE digital library databases for original articles regarding the effects of LLLT on osteoblast-like cells in experimental models using LLLT published in English from the last 20 years. The search identified 1439 studies. After the analysis of the abstracts, 1409 studies were excluded and 30 studies were then selected for the full-text analysis, 8 of which were excluded. Thus, 22 studies were included for a critical evaluation of the impact of photobiomodulation on osteoblast-like cell culture. The cell lineages studied were primary rat, primary human, saos-2, Osteo-1, MC3T3, MG63, and OFCOL II. Moreover, a wide variety of experimental models were used to experimentally analyze the impact of photobiomodulation, the most common of which were alkaline phosphatase, MTT, and cell count. This review suggests that osteoblastic-like cells are susceptible to photobiomodulation but that most of the light parameters varied by different authors have little to no influence on proliferation but very high levels of irradiance have demonstrated deleterious effects on proliferation, highlighting the bi-phasic effect of photobiomodulation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 22%
Student > Bachelor 5 14%
Researcher 3 8%
Student > Postgraduate 3 8%
Student > Ph. D. Student 3 8%
Other 5 14%
Unknown 10 27%
Readers by discipline Count As %
Medicine and Dentistry 7 19%
Biochemistry, Genetics and Molecular Biology 4 11%
Nursing and Health Professions 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Unspecified 2 5%
Other 8 22%
Unknown 12 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2018.
All research outputs
#18,604,390
of 23,045,021 outputs
Outputs from Lasers in Medical Science
#881
of 1,319 outputs
Outputs of similar age
#257,533
of 331,462 outputs
Outputs of similar age from Lasers in Medical Science
#22
of 39 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,319 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,462 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.